Quick Escape: A 2 Day Itinerary for San Francisco
If you’re searching for the perfect 2 day itinerary for San Francisco, you’re in the right place. With just a weekend to explore, you’ll want a plan that helps you hit the highlights without feeling rushed or spending half your trip stuck in traffic. Whether you’re planning a couples escape or a girls’ trip, this guide will help you make the most of your time in one of California’s most iconic cities.
He Works So I Travel content may contain affiliate links for products I use and love. If you purchase after clicking one of these links, I’ll earn a small commission at no additional cost to you. For full details, please read my full affiliate disclosure here.
Planning Your 2 Day Itinerary for San Francisco
Let’s talk about a few things people think they know about San Francisco.
First, yes, the fog is real, but it’s not the whole story.
Mornings along the coast might start gray, but many neighborhoods warm up nicely by midday. Pack layers and you’ll be just fine.
And despite what you’ve heard, you don’t need a car here. San Francisco is compact, walkable, and has excellent public transportation. In fact, ditching the rental car might be the best decision you make—no circling for parking, no crazy city driving, just hop on a streetcar or call an Uber.
Another misconception? That San Francisco is all tech bros and startups. The truth is, this city has a soul. From historic neighborhoods and world-famous landmarks to diverse food scenes and street art that tells real stories, there’s way more to see here than corporate campuses.
I’ve passed through San Francisco in all kinds of ways—coming home from Hawaii, stopping in on the way to Carmel by the Sea, or using it as a launch point for a trip to Sonoma wine country. Every time I visit, I’m reminded how much this city has to offer, even in just 48 hours.
This 2 day itinerary for San Francisco is built from real experiences, clever tips, and the kind of local flavor you won’t find in a guidebook. It’s perfect for anyone who wants to explore the city’s charm, culture, and views, without wasting time or overspending.
Let’s get into it.
Getting Around San Francisco
Before we dive into the fun stuff, let’s discuss logistics, as getting in and around San Francisco can make or break your weekend if you don’t plan ahead. For a quick trip like this, timing is everything.
San Francisco International (SFO) is your best bet for flying in. It’s just 13 miles south of downtown, and the BART train will whisk you into the city in about 30 minutes. It’s way faster (and cheaper) than sitting in traffic or paying surge pricing for a ride-share.
Once you’re in the city, there’s no need for a car.
San Francisco’s public transportation network is solid. You can use BART for longer trips, Muni buses, and cable cars for zipping around town. I always grab a Clipper Card when I arrive; it makes hopping between systems seamless, and you don’t have to fumble for change.
My biggest advice is to download those transit apps in advance. The fewer surprises you have with logistics, the more time you’ll have for crab rolls, scenic views, and a cheeky wine tasting or two.
If you absolutely must rent a car, include anywhere from $40-$75 per day in your budget for parking. I have been successful in renting affordable cars from Discover Cars and Hotwire. I used it most recently for a same-day car rental in Seattle.
Where to Stay for Your 2 Days in San Francisco
Where you stay in San Francisco can set the tone for your whole trip, especially when you’ve only got two days to play with.
You want somewhere that puts you close to the action, doesn’t eat up your time getting from point A to B, and adds a little character to your experience.
If this is your first time in San Francisco (or you prefer the convenience of being centrally located), Union Square is a great home base. You can regularly find Union Square’s special events, such as the Blooms & Bubbles Bar Crawl or a free concert in the park, taking place.
You’re within walking distance of shops, theaters, restaurants, and public transportation, including those iconic cable cars.
I’ve stayed here before when I wanted to be in the middle of it all, and I loved being able to roll out of bed and be at the Ferry Building or Chinatown within minutes.
Westin St Francis San Francisco Hotel in Union Square
The Westin St. Francis San Francisco on Union Square is in a prime downtown location. The hotel has luxurious accommodations and easy access to iconic attractions.
It’s also part of Marriott Bonvoy’s loyalty program, so that you can earn points.
You can enjoy elegant rooms, an array of dining options, and modern amenities, making it an ideal choice for a memorable stay.
If you’re dreaming of bay views and a quieter vibe in the evenings, The Embarcadero is a lovely option.
It’s perfect if you enjoy a scenic morning coffee and want easy access to the piers and the Ferry Building Farmers’ Market.
The Embarcadero has a more leisurely pace but still keeps you connected.
The Hyatt Regency San Francisco has a lovely waterfront location in this area.
Just one word of advice? Book early.
San Francisco doesn’t do last-minute deals very well, especially on weekends. I like to use booking platforms that offer free cancellation, so I can lock in something early and then swap it out if I find a better deal later.
Day 1: Waterfront to Landmarks
Morning: Cable Cars & Fisherman’s Wharf
No itinerary for San Francisco is complete without experiencing the iconic cable cars. Not only a National Historic Landmark, but it is also a charming mode of transportation that adds a touch of nostalgia to your getaway.
As you hop aboard one of these classic vehicles, you’ll feel the excitement build as one of the last manually operated cable cars begins its journey through the city’s famous hills.
To ride the cable cars, your best bet is to go early in the morning. Hop on the Powell-Hyde cable car line to Ghirardelli Square. This is the most scenic route, winding past Nob Hill and Chinatown.
The fare for a single ride is $8 per person, making it an affordable and unforgettable adventure. Use the MuniMobile app to purchase your tickets online or buy a ticket using exact cash at select locations. You can find out more ticket information here.
Begin day one of your 2 day itinerary for San Francisco with a delightful breakfast at one of the local favorites, like Eight AM or Hollywood Cafe. Both are just a short walk from the cable car turnaround.
Visit San Francisco‘s Fisherman’s Wharf and Pier 39
After breakfast, head over to Fisherman’s Wharf, a must-visit destination for first-time visitors trying to see everything on a 2 day itinerary for San Francisco.
Yes, Fisherman’s Wharf is a little touristy, but it’s still worth a stroll.
As you stroll along the waterfront, you’ll be surrounded by sea lions at Pier 39, clam chowder in sourdough bowls, and fun street performers.
You will also find the Skystar Ferris Wheel here. This 150-foot-tall observation wheel, once in Golden Gate Park, offers unparalleled views.
It reminds me of the wheel on the Linq Promenade in Vegas and the wheel on Navy Pier in Chicago.
Lunch at Fisherman’s Wharf
After shopping and exploring the area, I recommend having lunch at Fisherman’s Wharf.
You will find the best lobster rolls at Fog Harbor Fish House, ranked by Yelp as one of the top 5 restaurants in San Francisco. The stunning views of the bay are worth a stop here.
Or, swing by Boudin Bakery for a bowl of clam chowder in one of their signature sourdough bowls. I mean, how can you not grab a sourdough loaf at the home of the original San Francisco sourdough?
Before leaving Pier 39, check out some fantastic spots to pick up an afternoon treat, like Trish’s Mini Donuts. You know I am a sucker for a donut!
Afternoon: Explore the City’s Unique Neighborhoods
On the first afternoon of your 2 day itinerary for San Francisco, I recommend visiting San Francisco’s unique neighborhoods.
When you have little time, taking a Hop On, Hop Off Bus Tour allows you to see more places without having to worry about finding directions and parking.
Plus, at this point in day one, your legs may feel those San Francisco hills!
The San Francisco Big Bus Tour covers iconic landmarks, including Lombard Street, one of the city’s most famous and curviest streets.
You can hop off at many of San Francisco’s most iconic stops. Visit the bustling Ferry Building, which houses over 50 food merchants and the city’s farmers’ market.
Stop at San Francisco’s Chinatown, the oldest in North America to explore alleys, grab a dim sum snack, or get custom fortunes at Golden Gate Fortune Cookie Factory.
Additionally, don’t miss the Coit Tower to enjoy the breathtaking 360-degree city views from the observation deck.
Finally, don’t miss out on the Haight Ashbury neighborhood, where you can see the row of Victorian homes called The Painted Ladies.
The Painted Ladies aren’t people but a quintessential San Francisco attraction near Alamo Square Park. You may remember them from the popular 80’s TV show intro, Full House.
With convenient stops and a flexible schedule, you can explore the city at your own pace while enjoying informative commentary and stunning views from the comfort of the open-top bus.
TRIP TIP: Pick up the bus tour at Pier 39 in front of the Hard Rock Cafe.
Evening: Dinner and Nightlife in North Beach
For dinner, head to North Beach, San Francisco’s Little Italy.
The pasta here is legit. Book a dinner reservation at Sotto Mare or Tratto, both charming Italian restaurants, which remind me of my best meals in Venice and Florence.
Afterwards, wander to City Lights Bookstore and then grab gelato at Lush Gelato. Everything is walkable, safe, and filled with music, from jazz clubs to quiet espresso spots.
Day 2: From the Bridge to the Rock
Take a nice morning walk to the charming Nob Hill neighborhood.
Grab breakfast at Mymy Coffee Shop, a cozy café that’s the perfect spot to fuel up before a day of exploration.
Mymy Coffee Shop is known for its mouth-watering dishes, including its signature Crab Cake Benedict, fluffy Lemon Ricotta Pancakes, and savory Chorizo Scramble.
It’s so good!
Golden Gate Bridge
You can’t come to San Francisco and not see the Golden Gate Bridge.
From breakfast, catch the free Presidio GO Shuttle at Van Ness and Union.
At Presidio National Park, you will get postcard worthy pictures of the Golden Gate Bridge and Alcatraz.
Pop into the Golden Gate Bridge visitor center to browse the small museum, grab a souvenir and learn a few fascinating bridge facts. (It was painted orange for visibility, not style. Go figure.)
If you are up for a bit of cardio, take the Batteries to Bluffs Trail hike for dramatic views. On the way back through the Main Post area, visit the Walt Disney Family Museum if you’re into animation history.
Pro tip: Weather near the bridge changes fast. Layers, people. Always.
Golden Gate Park
When you leave the Presidio, head to Golden Gate Park.
Spanning over 1,000 acres, this lush urban oasis features serene lakes, picturesque groves, a Japanese Tea Garden, a conservatory, and a range of recreational opportunities.
As you wander through the park, you’ll be captivated by the breathtaking San Francisco skyline, which provides a stunning backdrop.
For a unique and memorable experience, consider joining a Segway tour or renting a bike to navigate the park’s winding paths.
Afternoon: Iconic San Francisco Landmark
Spend the last day of your 2 day itinerary for San Francisco by experiencing the best of San Francisco with the Alcatraz Island Visit and San Francisco Bay Cruise. This fantastic adventure combines two essential city experiences.
Your day begins with a ferry ride to the infamous Alcatraz Island, where you can enter the Alcatraz Federal Penitentiary. As you listen to the informative audio guide, imagine the history made here.
After your Alcatraz visit, take a breathtaking San Francisco Bay cruise.
You’ll be treated to stunning views of Pier 39’s playful sea lions, the vibrant waterfront area, and the city’s impressive skyline.
This unique combination of experiences offers an unforgettable way to explore the rich history and beauty of San Francisco.
For an unforgettable evening, schedule a sunset cruise of the Bay Area to watch the San Francisco city lights appear.
Evening: Unwind with Dinner and a San Francisco Sunset
Spend the last evening at an iconic San Francisco restaurant.
The Franciscan Crab Restaurant, located on Pier 43 1/2 in the heart of Fisherman’s Wharf, is a true gem of San Francisco’s dining scene.
From the moment you step inside, you’ll be captivated by the stunning panoramic views of the bay, the Golden Gate Bridge, and Alcatraz Island. The warm, inviting atmosphere and friendly and attentive service create an unforgettable dining experience.
The combination of delicious food, breathtaking views, and top-notch service makes the Franciscan Crab Restaurant a must-visit destination for an unforgettable dining experience in San Francisco.
You won’t be disappointed by this iconic restaurant.
Travel Tips for Your San Francisco Itinerary
Take advantage of public transportation
Book popular attractions in advance
Pack layers and comfortable shoes
Enjoy Your 2 Days in San Francisco
Whether it’s your first visit or your fifth, this 2 day San Francisco itinerary lets you see iconic sights and enjoy unexpected moments.
You’ll be sure to create unforgettable memories with so many fun things to do, from exploring the bustling waterfront at Fisherman’s Wharf to biking across the iconic Golden Gate Bridge.
Enjoy the culinary scene, with mouth-watering options ranging from fresh seafood to authentic international cuisine.
This city is full of contrast—fog and sun, bustle and calm, old-world charm and tech-fueled innovation—and in just one weekend, you can soak in a little of each.
